A urinalysis showing both glucose and protein most likely indicates

• A. Dehydration
• B. Diabetes mellitus with possible kidney involvement
• C. Urinary tract infection
• D. Liver disease

Answer: (B)

Glucose in the urine means blood glucose has exceeded the kidney’s ability to reabsorb it, a situation called glycosuria. Protein in the urine indicates that the kidneys’ filtering units are letting larger molecules through, signaling possible kidney stress or damage. When both occur together, it points to diabetes mellitus with possible kidney involvement because chronic high blood sugar can harm the kidneys and cause both glycosuria and proteinuria. Dehydration by itself doesn’t usually cause glucose in urine, and a urinary tract infection doesn’t typically produce glycosuria unless there’s also high blood sugar; liver disease affects different markers. So the combination most strongly suggests diabetes mellitus with potential kidney involvement.